The behavioral data infrastructure layer for pediatric medicine. AI-guided art therapy, sound therapy, and community wellness — deployed at the bedside.
O2 stabilizes pediatric patients through personalized community wellness and AI-guided art and sound therapy — operating as a behavioral regulation layer inside the clinical environment.
Procedures proceed without escalation. Treatment becomes tolerable. And for the first time, real-world behavioral data is captured from inside pediatric care.
Up to 60–70% of pediatric patients experience severe distress during treatment — yet no infrastructure exists to capture it in real time.
Leading to sedation, delayed procedures, and disrupted care workflows. This remains a major blind spot in modern healthcare data infrastructure.
O2 captures real-world patient experience and treatment tolerance data directly during pediatric treatment, building the behavioral data layer for modern therapeutics and mental health.
O2 is a hospital-deployed digital therapeutics platform that improves pediatric treatment tolerance while generating real-world behavioral data on patient experience. Clinician-ready — deployable in under 10 seconds, designed to fit nurse routines.
Autonomic nervous system regulation through frequency-matched music, ocean soundscapes, and personalized auditory environments during procedures.
−15 pts distress avg / sessionGuided creative expression calibrated to developmental stage. Externalises distress, restores agency, and builds a longitudinal emotional record.
+3.2 pts mood liftRhythmic patterned breathing for pre-procedure preparation. Interrupts anticipatory panic loops and preserves cooperation during imaging and infusion.
Tolerance 40% → 90%Structured peer matching, family co-presence tools, and caregiver alignment. The single highest-impact intervention in the O2 dataset.
−17 pts on session daysThis is O2.
Supports emotional expression and cognitive processing during care through guided creative art therapy. Grounded in clinical literature demonstrating reduced distress and increased treatment adherence in pediatric populations.
Maintains connection between patients, families, and peers to reduce isolation and stabilize experience during treatment. Peer connection is the single strongest predictor of psychological adaptation in adolescent cancer care.
Tracks behavioral recovery patterns and comfort levels over time to support safer, more tolerable care with guided AI support. Sound-based interventions grounded in auditory stimulation and autonomic nervous system regulation research.
Behavioral signals, self-reported mood, heart rate, stage of care, age profile, and caregiver interaction state are captured continuously.
Real-time personalization, predictive intolerance risk modeling, and dynamic intervention pacing route each patient to the right module at the right moment.
Reduced distress index, lower HR, fewer escalations, improved procedure tolerance, and a structured behavioral dataset for clinical reporting and research.
Music therapy during lumbar puncture in pediatric oncology produces pain reduction d=1.53 — among the largest effect sizes in any pediatric pain intervention. Rhythmic auditory stimulation entrains autonomic nervous system oscillations.
Produces greater mood improvement than music therapy in hospitalized children. Externalising distress into a created object restores the sense of agency disrupted by surgical trauma.
Patterned rhythmic breathing activates primitive brainstem regulation regions, bypassing higher cortical threat-processing centres. Headspace RCTs show acute stress reduction in clinical settings.
Peer and social support is the single strongest predictor of successful psychological adaptation in adolescent cancer. Social buffering attenuates HPA axis reactivity with measurable cortisol reduction during procedures.
O2 is purpose-built for the clinical environment — from oncology wards to cardiac units. Each deployment is adapted to the distress profile of that specialty's patients.
60–70% of pediatric oncology patients experience severe procedural distress. Chemo and lumbar punctures trigger anticipatory anxiety loops that escalate across treatment cycles.
Sound therapy during infusion, art therapy between cycles, community peer matching, and breathing protocols pre-lumbar puncture. Distress drops from 3 sedation events to 0 by Month 5.
Cardiac procedures trigger acute procedural anxiety compounded by chronic illness stress. Pre-procedure heart rate elevation directly affects procedure success rates and sedation requirements.
Breathing regulation protocols pre-catheterization, sound therapy during imaging, and caregiver co-presence tools. Autonomic nervous system priming before procedures reduces escalation events.
MRI and CT anxiety affects 80%+ of pediatric patients. O2 primes calm before the scanner and maintains it throughout.
Pre-operative anxiety spikes in the 24 hours before surgery. Breathing and sound protocols reduce anticipatory distress before anesthesia.
Prolonged stays and invasive monitoring create sustained distress. Community and sound modules maintain psychological stability during extended care.
Recovery phases carry their own psychological burden. O2 builds wellbeing habits during rehab that sustain long-term treatment adherence.
The innovation is not in inventing new science — it's in integrating validated modalities into a scalable clinical infrastructure platform.
Gradual nervous system stabilization before care begins via polyvagal theory-aligned interventions. Reduces anticipatory distress that spikes up to 24 hours before procedures.
Anchored attention pathways during imaging, infusion, or exams. Interrupts panic loops and preserves cooperation by deploying competing attentional resources through creative stimuli.
Keeps patients, families, and clinicians emotionally in sync to enable smoother treatment experiences. Co-regulation guidance built into the clinical workflow.
Continuously captures point-of-care behavioral signals — engagement, mood, HR, physiological markers — generating a composite distress index and tracking intervention response over time.
O2 is a hospital-deployed digital therapeutics platform that stabilizes pediatric patients through AI-guided art therapy, sound therapy, breathing exercises, and community wellness — while generating real-world behavioral data on patient experience during treatment.
O2 is designed for any pediatric unit where procedural distress occurs: oncology, cardiology, radiology and imaging, surgical prep, ICU, and rehabilitation. Each deployment is calibrated to the specific distress profile of the unit's patients, aged 5–16.
O2 is designed for bedside deployment in under 10 seconds by a nurse. It runs on tablets or mobile devices and integrates into existing care protocols — imaging prep, chemo sessions, recovery — without disrupting clinical workflow. Full hospital rollout includes implementation services, care team training, and outcome reporting setup.
O2 is sold on an annual contract basis per hospital unit. Pilot unit contracts start at €40K/year. Full hospital deployments range from €150K–€260K/year. Health system enterprise agreements are €400K–€1.2M+. A one-time implementation services fee of €40K–€50K applies.
O2 is built on four validated therapeutic modalities: music and sound therapy (Polyvagal Theory, Nguyen et al. 2010 — d=1.53 pain reduction), art therapy (Regev & Cohen-Yatziv 2018), patterned breathing and mindfulness, and community/peer connection (Varni et al. 1996 — the single strongest predictor of adaptation in adolescent cancer). The platform integrates these into a scalable AI-adaptive clinical infrastructure.
O2 captures real-time behavioral signals during therapeutic sessions — self-reported mood, engagement patterns, physiological markers like heart rate — to generate a composite distress index and track intervention response over time. This data is used to personalize care and, in aggregate (de-identified), to build the first large-scale behavioral dataset on pediatric treatment experience.
For hospitals, health systems, researchers, and investors. O2 sits at the intersection of digital therapeutics, pediatric care, and behavioral data infrastructure.
www.o2inc.co · o2@o2inc.co · Carrington Calloway, Founder & CEO